Tuberculosis
Volume 91 , Pages S142-S149 , December 2011

The β-propeller gene Rv1057 of Mycobacterium tuberculosis has a complex promoter directly regulated by both the MprAB and TrcRS two-component systems

  • Xiuhua Pang

      Affiliations

    • The State Key Lab of Microbial Technology, Shandong University, Jinan 250100, China
    • Center for Pulmonary and Infectious Disease Control, University of Texas Health Science Center at Tyler, Tyler, TX 75708, USA
    • Corresponding Author InformationCorresponding author. The State Key Lab of Microbial Technology, Shandong University, 27 Shanda Nanlu, Jinan 250100, Shandong Province, China. Tel.: + 86 531 88364590.
    • ,
  • Guangxiang Cao

      Affiliations

    • The State Key Lab of Microbial Technology, Shandong University, Jinan 250100, China
    • ,
  • Pierre F. Neuenschwander

      Affiliations

    • Department of Biochemistry, University of Texas Health Science Center at Tyler, Tyler, TX 75708, USA
    • ,
  • Shelley E. Haydel

      Affiliations

    • The Biodesign Institute Center for Infectious Diseases and Vaccinology, and School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA
    • ,
  • Guihua Hou

      Affiliations

    • The State Key Lab of Microbial Technology, Shandong University, Jinan 250100, China
    • ,
  • Susan T. Howard

      Affiliations

    • Center for Pulmonary and Infectious Disease Control, University of Texas Health Science Center at Tyler, Tyler, TX 75708, USA
    • Department of Microbiology, University of Texas Health Science Center at Tyler, Tyler, TX 75708, USA
    • Corresponding Author InformationCorresponding author. D617, Biomedical Research, UTHSCT, 11937 U.S. Highway 271, Tyler, TX 75708-3154, USA. Tel.: +1 903 877 7684; fax: +1 903 877 7989.

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☆ While our manuscript was under review, the Zahrt laboratory reported that MprAB and DosRST coregulate the Rv0081-Rv0088 operon (He H, Bretl DJ et al., 2011, J. Bact. 193:5105-5118), providing further evidence for coordinated regulation of stress response genes by TCSs.

PII: S1472-9792(11)00194-6

doi: 10.1016/j.tube.2011.10.024

Tuberculosis
Volume 91 , Pages S142-S149 , December 2011

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